TY - JOUR AU - Song, Jun S AB - Abstract ChIP-seq is a powerful method for obtaining genome-wide maps of protein-DNA interactions and epigenetic modifications. CHANCE (CHip-seq ANalytics and Confidence Estimation) is a standalone package for ChIP-seq quality control and protocol optimization. Our user-friendly graphical software quickly estimates the strength and quality of immunoprecipitations, identifies biases, compares the user's data with ENCODE's large collection of published datasets, performs multi-sample normalization, checks against quantitative PCR-validated control regions, and produces informative graphical reports. CHANCE is available at https://github.com/songlab/chance. TI - CHANCE: comprehensive software for quality control and validation of ChIP-seq data JF - Genome Biology DO - 10.1186/gb-2012-13-10-r98 DA - 2012-10-01 UR - https://www.deepdyve.com/lp/springer-journals/chance-comprehensive-software-for-quality-control-and-validation-of-P5tItoOr70 SP - 1 EP - 15 VL - 13 IS - 10 DP - DeepDyve ER -