TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 276, No. 47, Issue of November 23, pp. 43564 –43569, 2001 © 2001 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. Preferential ATP-binding Cassette Transporter A1-mediated Cholesterol Efflux from Late Endosomes/Lysosomes* Received for publication, August 17, 2001, and in revised form, September 13, 2001 Published, JBC Papers in Press, September 14, 2001, DOI 10.1074/jbc.M107938200 Wengen Chen‡, Yu Sun‡, Carrie Welch, Anna Gorelik, Andrew R. Leventhal, Ira Tabas, and Alan R. Tall§ From the Division of Molecular Medicine, Department of Medicine, Columbia University, New York, New York 10032 Recently, ATP-binding cassette transporter A1 phages from these animals have a profound defect in apoA-I- (ABCA1), the defective molecule in Tangier disease, has mediated cholesterol efflux (8 –10), indicating that apolipopro- been shown to stimulate phospholipid and cholesterol tein-mediated cholesterol efflux is primarily mediated by efflux to apolipoprotein A-I (apoA-I); however, little is ABCA1. In contrast, ABCA1 shows only slight interaction with known concerning the cellular cholesterol pools that act HDL and no interaction with HDL (11). Cellular cholesterol 3 2 as the source of cholesterol for ABCA1-mediated efflux. efflux mediated by HDL is thought to involve a “passive” proc- We 
TI - Preferential ATP-binding Cassette Transporter A1-mediated Cholesterol Efflux from Late Endosomes/Lysosomes
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.m107938200
DA - 2001-11-01
UR - https://www.deepdyve.com/lp/unpaywall/preferential-atp-binding-cassette-transporter-a1-mediated-cholesterol-PV06SdrWzz
DP - DeepDyve
ER -