TY - JOUR AU1 - de Castro, Roberta Esteves Vieira AU2 - Medeiros, Daniela Nasu Monteiro AU3 - Prata-Barbosa, Arnaldo AU4 - de Magalhães-Barbosa, Maria Clara AB - Letters to the Editor This work was performed at School of Medicine and Pedi- The authors reply: atric Intensive Care of Hospital São Lucas, Pontifical Catholic e appreciate the interest of Awasthi and Angurana University of Rio Grande do Sul (PUCRS), Brazil. (1) in our findings recently published in Pediatric WCritical Care Medicine (2). We agree that according Cristian T. Tonial, PhD, Department of Pediatrics, School of Medicine and Pediatric Intensive Care of Hospital São to the current definition criteria, hyperferritinemic sepsis and Lucas, Pontifical Catholic University of Rio Grande do Sul hemophagocytic syndrome or hemophagocytic lymphohistio- (PUCRS), Porto Alegre, RS, Brazil; Pedro Celiny R. Garcia, cytosis (HLH) syndrome may have overlapping characteristics PhD, Department of Pediatrics, Post-graduate Program in or may even represent different spectra of the same inflamma- Pediatrics and Child Health, School of Medicine and Pediatric tory process (3). Intensive Care of Hospital São Lucas, Pontifical Catholic We constantly suspect the possibility of secondary HLH in University of Rio Grande do Sul (PUCRS), Brazilian Council our clinical practice. Since 2007 when Garcia et al (4) showed for Scientific and Technological Development (CNPq), Porto Alegre, RS, Brazil the association of hyperferritinemia with unfavorable out- comes in critical TI - Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children JF - Pediatric Critical Care Medicine DO - 10.1097/PCC.0000000000002444 DA - 2020-10-01 UR - https://www.deepdyve.com/lp/wolters-kluwer-health/surviving-sepsis-campaign-international-guidelines-for-the-management-S5VKwcoH0o SP - 924 EP - 925 VL - 21 IS - 10 DP - DeepDyve ER -