TY - JOUR
AU - Wong, Wing Hung
AB - Chromatin immunoprecipitation (ChIP) coupled with genome tiling array hybridization (ChIP‐chip) and ChIP followed by massively parallel sequencing (ChIP‐seq) are high‐throughput approaches to profiling genome‐wide protein‐DNA interactions. Both technologies are increasingly used to study transcription‐factor binding sites and chromatin modifications. CisGenome is an integrated software system for analyzing ChIP‐chip and ChIP‐seq data. This unit describes basic functions of CisGenome and how to use them to find genomic regions with protein‐DNA interactions, visualize binding signals, associate binding regions with nearby genes, search for novel transcription‐factor binding motifs, and map existing DNA sequence motifs to user‐supplied genomic regions to define their exact locations.Curr. Protoc. Bioinform. 33:2.13.1‐2.13.45. © 2011 by John Wiley & Sons, Inc.
TI - Using CisGenome to Analyze ChIP‐chip and ChIP‐seq Data
JF - Current Protocols in Bioinformatics
DO - 10.1002/0471250953.bi0213s33
DA - 2011-03-01
UR - https://www.deepdyve.com/lp/wiley/using-cisgenome-to-analyze-chip-chip-and-chip-seq-data-SRQtp0PPuO
SP - 2.13.1
EP - 2.13.45
VL - 33
IS - 1
DP - DeepDyve
ER -