TY - JOUR
AU - Shirouzu, K.
AB - Int J Clin Oncol (2001) 6:221–228 © The Japan Society of Clinical Oncology 2001 ORIGINAL ARTICLE Yoshikazu Harada · Yutaka Ogata · Kazuo Shirouzu Expression of vascular endothelial growth factor and its receptor KDR (kinase domain-containing receptor)/Flk-1 (fetal liver kinase-1) as prognostic factors in human colorectal cancer Received: September 18, 2000 / Accepted: August 27, 2001 Abstract angiogenesis. VEGF and its receptor KDR expression in Background . To clarify the clinical significance of the ex- tumorous tissues could be useful prognostic factors in pression of vascular endothelial growth factor (VEGF) and colorectal cancer. its receptor, kinase domain-containing receptor (KDR) in colorectal cancer, we evaluated the relationship between Key words Vascular endothelial growth factor (VEGF) · KDR (kinase domain-containing receptor)/Flk-1 (fetal the expression of VEGF and KDR, and the microvessel counts and clinicopathological factors in colorectal cancer. liver kinase-1) · Immunohistochemistry · Microvessel count (microvessel density) · Prognostic factor · Colorectal cancer Methods. A total of 259 specimens from sequential colorectal cancer patients who had undergone surgery were examined by the avidin-biotin peroxidase complex method, using anti-human VEGF, anti-human KDR, and Introduction anti-human von Willebrand factor antibodies. Results. The incidence of VEGF expression in the tumor 1–2 cells of the 
TI - Expression of vascular endothelial growth factor and its receptor KDR (kinase domain-containing receptor)/Flk-1 (fetal liver kinase-1) as prognostic factors in human colorectal cancer
JF - International Journal of Clinical Oncology
DO - 10.1007/PL00012109
DA - 2001-10-01
UR - https://www.deepdyve.com/lp/springer-journals/expression-of-vascular-endothelial-growth-factor-and-its-receptor-kdr-SaSxoafqR4
SP - 221
EP - 228
VL - 6
IS - 5
DP - DeepDyve
ER -