TY - JOUR
AU - DeFries, J.
AB - In order to test the hypothesis that the genetic etiology of reading disability differs as a function of IQ, composite reading performance data from 308 pairs of identical (monozygotic, MZ) twins and 440 pairs of fraternal (dizygotic, DZ) twins (254 same-sex and 186 opposite-sex) in which at least one member of each pair was classified as reading-disabled were subjected to multiple regression analysis  (DeFries and Fulker, Behav Genet 15:467–473, 1985; Acta Genet Med Gemellol 37:205–216, 1988). In the total sample, heritability of the group deficit in reading performance (h
g
2
) was .61 (±.06). However, results of fitting an extended regression model to reading performance and IQ data suggested that the genetic etiology of reading disability differs as a linear function of IQ (p ≤ .04). When the basic regression model was fitted separately to data from twin pairs with Wechsler (Examiner's manual: Wechsler intelligence scale for children—revised, 1974; Examiner's manual: Wechsler adult intelligence scale—revised, 1981) Full Scale IQ scores in the upper and lower 25% of the sample, resulting estimates of h
g
2
 were .75 (±.12) and .50 (±.10), respectively (p ≤ .045). These results suggest that reading difficulties in children with a higher IQ are due substantially to genetic influences and may require intensive remediation efforts.
TI - Differential Genetic Etiology of Reading Difficulties as a Function of IQ: An Update
JF - Behavior Genetics
DO - 10.1007/s10519-010-9349-x
DA - 2010-03-24
UR - https://www.deepdyve.com/lp/springer-journals/differential-genetic-etiology-of-reading-difficulties-as-a-function-of-SbCUUXyjIY
SP - 751
EP - 758
VL - 40
IS - 6
DP - DeepDyve
ER -