TY - JOUR AU - Merchant, Thomas E AB - Objective:A ceiling-mounted robotic C-arm cone beam CT (CBCT) system was developed for use with a 190° proton gantry system and a 6-degree-of-freedom robotic patient positioner. We report on the mechanical design, system accuracy, image quality, image guidance accuracy, imaging dose, workflow, safety and collision-avoidance.Methods:The robotic CBCT system couples a rotating C-ring to the C-arm concentrically with a kV X-ray tube and a flat-panel imager mounted to the C-ring. CBCT images are acquired with flex correction and maximally 360° rotation for a 53 cm field of view. The system was designed for clinical use with three imaging locations. Anthropomorphic phantoms were imaged to evaluate the image guidance accuracy.Results:The position accuracy and repeatability of the robotic C-arm was high (<0.5 mm), as measured with a high-accuracy laser tracker. The isocentric accuracy of the C-ring rotation was within 0.7 mm. The coincidence of CBCT imaging and radiation isocentre was better than 1 mm. The average image guidance accuracy was within 1 mm and 1° for the anthropomorphic phantoms tested. Daily volumetric imaging for proton patient positioning was specified for routine clinical practice.Conclusion:Our novel gantry-independent robotic CBCT system provides high-accuracy volumetric image guidance for proton therapy.Advances in knowledge:Ceiling-mounted robotic CBCT provides a viable option than CT on-rails for partial gantry and fixed-beam proton systems with the added advantage of acquiring images at the treatment isocentre. TI - A robotic C-arm cone beam CT system for image-guided proton therapy: design and performance JF - British Journal of Radiology DO - 10.1259/bjr.20170266 DA - 2017-10-09 UR - https://www.deepdyve.com/lp/oxford-university-press/a-robotic-c-arm-cone-beam-ct-system-for-image-guided-proton-therapy-SckPexfLH8 VL - 90 IS - 1079 DP - DeepDyve ER -