TY - JOUR AU - AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 279, No. 44, Issue of October 29, pp. 46304–46314, 2004 © 2004 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. A Novel Snake Venom Vascular Endothelial Growth Factor (VEGF) Predominantly Induces Vascular Permeability through Preferential Signaling via VEGF Receptor-1* Received for publication, April 2, 2004, and in revised form, July 14, 2004 Published, JBC Papers in Press, August 24, 2004, DOI 10.1074/jbc.M403687200 Hiroyuki Takahashi‡§, Shosaku Hattori , Akihiro Iwamatsu , Hajime Takizawa§, and Masabumi Shibuya‡** From the ‡Division of Genetics, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokane-dai, Minato-ku, Tokyo 108-8639, Japan, the §Department of Internal Medicine, Graduate School of Medicine, University of Tokyo, Tokyo 113- 8655, Japan, the Amami Laboratory of Injurious Animals, Institute of Medical Science, University of Tokyo, Kagoshima 894-1531, Japan, and the Central Laboratories for Key Technology, Kirin Brewery Company Limited, Yokohama 236-0004, Japan essential for many angiogenic processes in normal and abnor- Vascular endothelial growth factor (VEGF)/vascular permeability factor induces both angiogenesis and vas- mal states such as tumor vascularization (1). VEGF-A exhibits cular permeability mainly through VEGF receptor two major biological activities: one is the capacity to stimulate (VEGFR)-2 activation. VEGF TI - A Novel Snake Venom Vascular Endothelial Growth Factor (VEGF) Predominantly Induces Vascular Permeability through Preferential Signaling via VEGF Receptor-1 JF - Journal of Biological Chemistry DO - 10.1074/jbc.m403687200 DA - 2004-10-01 UR - https://www.deepdyve.com/lp/unpaywall/a-novel-snake-venom-vascular-endothelial-growth-factor-vegf-T23czfeaUL DP - DeepDyve ER -