TY - JOUR AU - Alessandro, Sette AB - A planned repository of immune epitope data with associated analysis tools should be a boon to vaccine development. Introduction Recent concerns about bioterrorism and emerging diseases have led to a new focus on the development of vaccines and drugs targeting infectious pathogens. An important component of vaccine development is the characterization of immune responses (to vaccination, for example, or following infection in experimental settings) by evaluating the epitopes recognized by antigen-specific receptors of the immune system (antibodies and/or T cell receptors (TCRs)) [ 1 ]. In recent years, different groups have followed different approaches to the discovery of immune epitopes, and various assay types have been used to generate data for the purpose of epitope definition or validation. We believe that research in this area could be greatly facilitated by a comprehensive knowledge center: a repository of immune epitope data with associated analysis tools. Our goal is the creation of the Immune Epitope Database and Analysis Resource (IEDB). The IEDB is sponsored by the National Institute for Allergy and Infectious Diseases (NIAID). It will host data relating to both B cell and T cell epitopes from infectious pathogens, as well as experimental and self-antigens (RTP-NIH-NIAID-DAIT-03/31; www.niaid.nih.gov/contract/archive ). Priority TI - The Immune Epitope Database and Analysis Resource: From Vision to Blueprint JF - PLoS Biology DO - 10.1371/journal.pbio.0030091 DA - 2005-03-15 UR - https://www.deepdyve.com/lp/public-library-of-science-plos-journal/the-immune-epitope-database-and-analysis-resource-from-vision-to-TOFOjZRxjo VL - 3 IS - 3 DP - DeepDyve ER -