TY - JOUR AU - Gilmore, T D AB - This article serves as an introduction to the collection of reviews on nuclear factor-kappaB (NF-κB). It provides an overview of the discovery and current status of NF-κB as a research topic. Described are the structures, activities and regulation of the proteins in the NF-κB family of transcription factors. NF-κB signaling is primarily regulated by inhibitor κB (IκB) proteins and the IκB kinase complex through two major pathways: the canonical and non-canonical NF-κB pathways. The organization and focus of articles included in the following reviews are described, as well as likely future areas of research interest on NF-κB. TI - Introduction to NF-κB: players, pathways, perspectives JF - Oncogene DO - 10.1038/sj.onc.1209954 DA - 2006-10-30 UR - https://www.deepdyve.com/lp/springer-journals/introduction-to-nf-b-players-pathways-perspectives-V5Q2NLI6Mg SP - 6680 EP - 6684 VL - 25 IS - 51 DP - DeepDyve ER -