TY - JOUR
AU - Unemo, Magnus
AB - 
We describe the first case of treatment failure of gonorrhoea with a third generation cephalosporin, cefotaxime 1g intramuscularly, in the Netherlands. The case was from a high-frequency transmitting population (men having sex with men) and was caused by the internationally spreading multidrug-resistant gonococcal NG-MAST ST1407 clone. The patient was clinically cured after treatment with ceftriaxone 500 mg intramuscularly and this is the only third generation cephalosporin that should be used for first-line empiric treatment of gonorrhoea. Increased awareness of failures with third generation cephalosporins, enhanced monitoring and appropriate verification of treatment failures including more frequent test-of-cures, and strict adherence to regularly updated treatment guidelines are essential globally.

TI - Verified clinical failure with cefotaxime 1g for treatment of gonorrhoea in the Netherlands: a case report
JF - Sexually Transmitted Infections
DO - 10.1136/sextrans-2014-051552
DA - 2014-11-11
UR - https://www.deepdyve.com/lp/british-medical-journal/verified-clinical-failure-with-cefotaxime-1g-for-treatment-of-VA4nVq2UTM
SP - 513
EP - 514
VL - 90
IS - 7
DP - DeepDyve
ER -