TY - JOUR AU - Nicholls, Philip K. AB - The First Complete Papillomavirus Genome Characterized from a Marsupial Host: a Novel Isolate from Bettongia penicillata ▿ Mark D. Bennett 1 , * , Andrea Reiss 2 , Hans Stevens 3 , Elisabeth Heylen 3 , Marc Van Ranst 3 , Adrian Wayne 4 , Michael Slaven 1 , Jennifer N. Mills 1 , Kristin S. Warren 1 , Amanda J. O'Hara 1 and Philip K. Nicholls 1 1 School of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, Western Australia 6150, Australia 2 Perth Zoo, 20 Labouchere Road, South Perth, Western Australia 6951, Australia 3 Laboratory of Clinical and Epidemiological Virology, Department of Microbiology and Immunology, Rega Institute for Medical Research, University of Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium 4 Science Division, Department of Environment and Conservation, Brain Street, Manjimup, Western Australia 6258, Australia ABSTRACT The first fully sequenced papillomavirus (PV) of marsupials, tentatively named Bettongia penicillata papillomavirus type 1 (BpPV1), was detected in papillomas from a woylie ( Bettongia penicillata ogilbyi ). The circular, double-stranded DNA genome contains 7,737 bp and encodes 7 open reading frames (ORFs), E6 , E7 , E1 , E2 , E4 , L2 , and L1 , in typical PV conformation. BpPV1 is a close-to-root PV with L1 and L2 ORFs most similar to European hedgehog PV and bandicoot papillomatosis carcinomatosis virus types 1 and 2 (BPCV1 and -2). It appears that the BPCVs arose by recombination between an ancient PV and an ancient polyomavirus more than 10 million years ago. TI - The First Complete Papillomavirus Genome Characterized from a Marsupial Host: a Novel Isolate from Bettongia penicillata JF - Journal of Virology DO - 10.1128/JVI.02635-09 DA - 2010-05-15 UR - https://www.deepdyve.com/lp/american-society-for-microbiology/the-first-complete-papillomavirus-genome-characterized-from-a-VMhvb4Wsd5 SP - 5448 VL - 84 IS - 10 DP - DeepDyve ER -