TY - JOUR
AB - AbstractWe expand our previous deterministic power calculations by calculating the required sample size to detect C in ACE models. The theoretical expected value of the maximum log-likelihood for the AE model was derived using two optimisation methods and these gave near-identical results. Theoretical predictions were verified by computer simulation and the results agreed very well. We have developed a user-friendly web-based tool, TwinPower, to perform power calculations to detect either A or C for the classical twin design. This new tool can be found at http://genepi.qimr.edu.au/cgi-bin/twinpower.cgi
TI - Power of the Classical Twin Design Revisited: II Detection of Common Environmental Variance
JF - Twin Research and Human Genetics
DO - 10.1375/twin.11.1.48
DA - 2012-02-21
UR - https://www.deepdyve.com/lp/cambridge-university-press/power-of-the-classical-twin-design-revisited-ii-detection-of-common-VQzIXGjfZ6
SP - 48
EP - 54
VL - 11
IS - 1
DP - DeepDyve
ER -