TY - JOUR
AU - 
AB - REVIEW ARTICLE published: 05 March 2014 doi: 10.3389/fendo.2014.00026 Biophysical detection of diversity and bias in GPCR function 1 † 1 † 2 1,3 Werner C. Jaeger , Stephen P. Armstrong , Stephen J. Hill and Kevin D. G. Pfleger * Molecular Endocrinology and Pharmacology, Harry Perkins Institute of Medical Research and Centre for Medical Research, The University of Western Australia, Perth, WA, Australia Cell Signalling Research Group, School of Life Sciences, Queen’s Medical Centre, University of Nottingham Medical School, Nottingham, UK Dimerix Bioscience Pty Ltd, Perth, WA, Australia Edited by: Guanine nucleotide binding protein (G protein)-coupled receptors (GPCRs) function in com- Stuart Maudsley, National Institutes plexes with a range of molecules and proteins including ligands, G proteins, arrestins, of Health, USA ubiquitin, and other receptors. Elements of these complexes may interact constitutively or Reviewed by: dynamically, dependent upon factors such as ligand binding, phosphorylation, and dephos- Emma June Petrie, The University of phorylation. They may also be allosterically modulated by other proteins in a manner Melbourne, Australia Joris Hubertus Robben, Radboud that changes temporally and spatially within the cell. Elucidating how these complexes University Nijmegen Medical Centre, function has been greatly enhanced by biophysical technologies that are able to 
TI - Biophysical Detection of Diversity and Bias in GPCR Function
JF - Frontiers in Endocrinology
DO - 10.3389/fendo.2014.00026
DA - 2014-03-05
UR - https://www.deepdyve.com/lp/unpaywall/biophysical-detection-of-diversity-and-bias-in-gpcr-function-WSdhMaO9Rx
DP - DeepDyve
ER -