TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 277, No. 29, Issue of July 19, pp. 26120 –26127, 2002 © 2002 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. The T-box Repressors TBX2 and TBX3 Specifically Regulate the ARF Tumor Suppressor Gene p14 via a Variant T-site in the Initiator* Received for publication, January 14, 2002, and in revised form, May 7, 2002 Published, JBC Papers in Press, May 8, 2002, DOI 10.1074/jbc.M200403200 Merel E. Lingbeek‡, Jacqueline J. L. Jacobs§, and Maarten van Lohuizen¶ From the Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands ARF ARF The murine tumor suppressor p19 T-site as a dimer (7). Of all T-box genes only three, TBX2, TBX3 (p14 in hu- mans) is thought to fulfill an important protective role and Xenopus ET, are currently known to be transcriptional in preventing primary cells from oncogenic transforma- repressors, probably acting via a putative repression domain tion via its action in the p53 pathway. Several disease- (8, 9). TBX2 was shown to act on the melanocyte-specific TRP-1 ARF implicated regulators of p19 are known to date, promoter, not by a regular T-site but by two 
TI - The T-box Repressors TBX2 and TBX3Specifically Regulate the Tumor Suppressor Genep14 via a Variant T-site in the Initiator
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.m200403200
DA - 2002-07-01
UR - https://www.deepdyve.com/lp/unpaywall/the-t-box-repressors-tbx2-and-tbx3specifically-regulate-the-tumor-Y7Yh00HFYS
DP - DeepDyve
ER -