TY - JOUR
AU1 - Simoni, Jane
AU2 - Chen, Wei-Ti
AU3 - Huh, David
AU4 - Fredriksen-Goldsen, Karen
AU5 - Pearson, Cynthia
AU6 - Zhao, Hongxin
AU7 - Shiu, Cheng-Shi
AU8 - Wang, Xin
AU9 - Zhang, Fujie
AB - We evaluated a nurse-delivered adherence intervention in a preliminary randomized controlled trial among 70 HIV-positive outpatients initiating antiretroviral therapy (ART) in Beijing, China. In both arms, participants received a 30-min educational session, a pillbox, and a referral to a peer support group. In the enhanced arm, participants could choose an electronic reminder device, three sessions of counseling either alone or with a treatment adherence partner, or both reminder and counseling. Survey assessments and blood draws occurred at baseline, post-intervention (13 weeks), and follow-up (25 weeks). Primary outcomes were 7-day and 30-day adherence assessed by self-report and electronic drug monitoring (EDM), and secondary outcomes were HIV-1 RNA viral load and CD4 count. The intervention was feasible and well received. It led to some improvement in self-reported and EDM-assessed adherence but not the biological outcomes. Providing counseling and facilitating the use of electronic reminders to patients initiating ART merits further investigation as a culturally viable means of promoting adherence in China.
TI - A Preliminary Randomized Controlled Trial of a Nurse-Delivered Medication Adherence Intervention Among HIV-Positive Outpatients Initiating Antiretroviral Therapy in Beijing, China
JF - AIDS and Behavior
DO - 10.1007/s10461-010-9828-3
DA - 2010-10-19
UR - https://www.deepdyve.com/lp/springer-journals/a-preliminary-randomized-controlled-trial-of-a-nurse-delivered-YNIk09Qb0E
SP - 919
EP - 929
VL - 15
IS - 5
DP - DeepDyve
ER -