TY - JOUR
AU - Lindahl, Tomas
AB - Although DNA is the carrier of genetic information, it has limited chemical stability. Hydrolysis, oxidation and nonenzymatic methylation of DNA occur at significant ratesin vivo, and are counteracted by specific DNA repair processes. The spontaneous decay of DNA is likely to be a major factor in mutagenesis, carcinogenesis and ageing, and also sets limits for the recovery of DNA fragments from fossils.
TI - Instability and decay of the primary structure of DNA
JF - Nature
DO - 10.1038/362709a0
DA - 1993-04-22
UR - https://www.deepdyve.com/lp/springer-journals/instability-and-decay-of-the-primary-structure-of-dna-ZZBHPl40b0
SP - 709
EP - 715
VL - 362
IS - 6422
DP - DeepDyve
ER -