TY - JOUR
AU - Bergua, A
AB - LABORATORY STUDY Eye (2017) 31, 1496–1502 © 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved 0950-222X/17 www.nature.com/eye B Hohberger, C Baumgart and A Bergua Optical clearing of the eye using the See Deep Brain technique Abstract Introduction Purpose Tissue clearing has been used in Tissue clearing has been investigated for a long anatomy for the first time in Germany over a time. Already in 1914, Spalteholz reported for century ago. Neuronal tissue, like cortex, was the first time about a method for clarifying investigated in mice using a water-based tissues. Since then it was the aim of several optical clearing method termed See Deep investigators to look inside structures without Brain (SeeDB). However, although the eye opening them and therefore destroying their belongs to the central nervous system, this intrinsic anatomy by increasing transparency. histological technique was not applied in the For this purpose, it is necessary to minimize light eye up to date. We applied SeeDB for the scattering, which is caused by several internal visualization of intraocular structures. cellular structures (eg, membranes and nuclei) Patients and methods Four eyes of cornea and extracellular material (eg, extracellular donors (two male, two female: 73–84 years) matrix). 
TI - Optical clearing of the eye using the See Deep Brain technique
JF - Eye
DO - 10.1038/eye.2017.83
DA - 2017-06-02
UR - https://www.deepdyve.com/lp/springer-journals/optical-clearing-of-the-eye-using-the-see-deep-brain-technique-aM9g1TuscW
SP - 1496
EP - 1502
VL - 31
IS - 10
DP - DeepDyve
ER -