TY - JOUR AU - AB - Downloaded from genesdev.cshlp.org on May 29, 2022 - Published by Cold Spring Harbor Laboratory Press FACKEL is a sterol C-14 reductase required for organized cell division and expansion in Arabidopsis embryogenesis 1,6 1 2 3 4 Kathrin Schrick, Ulrike Mayer, Andrea Horrichs, Christine Kuhnt, Catherine Bellini, 2,5 3 1 Jeff Dangl, Ju ¨ rgen Schmidt, and Gerd Ju ¨ rgens 1 2 Zentrum fu ¨ r Molekularbiologie der Pflanzen, Universita ¨t Tu ¨ bingen, D-72076 Tu ¨ bingen, Germany; Max Delbru ¨ck 3 4 Laboratory, D-50858 Ko ¨ ln, Germany; Leibniz-Institut fu ¨ r Pflanzenbiochemie, D-06120 Halle/Saale, Germany; Laboratoire de Biologie Cellulaire, INRA, F-78026 Versailles Cedex, France In flowering plants, the developing embryo consists of growing populations of cells whose fates are determined in a position-dependent manner to form the adult organism. Mutations in the FACKEL (FK) gene affect body organization of the Arabidopsis seedling. We report that FK is required for cell division and expansion and is involved in proper organization of the embryo. We isolated FK by positional cloning. Expression analysis in embryos revealed that FK mRNA becomes localized to meristematic zones. FK encodes a predicted integral membrane protein related to the vertebrate lamin B receptor and TI - FACKEL is a sterol C-14 reductase required for organized cell division and expansion in Arabidopsis embryogenesis JF - Genes & Development DO - 10.1101/gad.14.12.1471 DA - 2000-06-15 UR - https://www.deepdyve.com/lp/unpaywall/fackel-is-a-sterol-c-14-reductase-required-for-organized-cell-division-bDBFRNSARu DP - DeepDyve ER -