TY - JOUR
AU1 - Krull, Mathias
AU2 - Voss, Nico
AU3 - Choi, Claudia
AU4 - Pistor, Susanne
AU5 - Potapov, Anatolij
AU6 - Wingender, Edgar
AB - TRANSPATH® is a database system about gene regulatory networks that combines encyclopedic information on signal transduction with tools for visualization and analysis. The integration with TRANSFAC®, a database about transcription factors and their DNA binding sites, provides the possibility to obtain complete signaling pathways from ligand to target genes and their products, which may themselves be involved in regulatory action. As of July 2002, the TRANSPATH Professional release 3.2 contains about 9800 molecules, >1800 genes and >11 400 reactions collected from ∼5000 references. With the ArrayAnalyzer™, an integrated tool has been developed for evaluation of microarray data. It uses the TRANSPATH data set to identify key regulators in pathways connected with up- or down-regulated genes of the respective array. The key molecules and their surrounding networks can be viewed with the PathwayBuilder™, a tool that offers four different modes of visualization. More information on TRANSPATH is available at http://www.biobase.de/pages/products/databases.html.
TI - TRANSPATH®: an integrated database on signal transduction and a tool for array analysis
JF - Nucleic Acids Research
DO - 10.1093/nar/gkg089
DA - 2003-01-01
UR - https://www.deepdyve.com/lp/oxford-university-press/transpath-an-integrated-database-on-signal-transduction-and-a-tool-for-c2aIg0XXxU
SP - 97
EP - 100
VL - 31
IS - 1
DP - DeepDyve
ER -