TY - JOUR AU - AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 276, No. 40, Issue of October 5, pp. 36865–36868, 2001 Minireview © 2001 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. tivators is associated with the AF-1 domain. As the number of Coregulator Codes of potential coregulators clearly exceeds the capacity for direct inter- action by a single receptor, the most plausible hypothesis is that Transcriptional Regulation transcriptional activation by nuclear receptors involves the actions by Nuclear Receptors* of multiple factors. These factors act in a sequential and/or combi- natorial manner to reorganize chromatin templates and to modify and recruit basal factors and RNA polymerase II (3, 4). Published, JBC Papers in Press, July 17, 2001, DOI 10.1074/jbc.R100041200 ATP-dependent Chromatin Remodeling Complexes Michael G. Rosenfeld‡§ and Christopher K. Glass As chromatinized transcription units are “repressed” compared with naked DNA, a critical aspect of gene activation involves nu- From the ‡Department and School of Medicine, cleosomal remodeling (reviewed in Refs. 3–5). Two general classes Howard Hughes Medical Institute, University of of chromatin remodeling factors that appear to play critical roles in California, San Diego, La Jolla, California 92095-0648 transcriptional activation by nuclear receptors have been identi- and ¶Department of TI - Coregulator Codes of Transcriptional Regulation by Nuclear Receptors JF - Journal of Biological Chemistry DO - 10.1074/jbc.r100041200 DA - 2001-10-01 UR - https://www.deepdyve.com/lp/unpaywall/coregulator-codes-of-transcriptional-regulation-by-nuclear-receptors-cpSAaf5fn8 DP - DeepDyve ER -