TY - JOUR AU1 - SIEPEL, ADAM C. AU2 - HALPERN, AARON L. AU3 - MACKEN, CATHERINE AU4 - KORBER, BETTE T.M. AU5 - AB - AIDS RESEARCH AND HUMAN RETROVIRUSES Volume Number 1995 11, 11, Ann Inc. Liebert, Mary Note Sequence A to Screen for HIV Computer Program Designed Rapidly 1 Recombinant Type Intersubtype Sequences ADAM AARON L. CATHERINE and KORBER C. BETTE T.M. SIEPEL, HALPERN, MACKEN, are across etection of recombinant the that conserved When the informative mode genomes involving genetically subtypes. Ddistinct HIV-1 is a current of immense is the RIP counts informative defined as active, subtypes problem only positions, if such recombination occurs with at which at least one consensus dif- importance1-3; intersubtype positions subtype sequence notable the formidable of devel- fers from the when it determines window boundaries in others, frequency, already challenge vaccines is further relation to a central or reference The second oping against multiple subtypes complicated. position. option Here we describe a and heuristic method for de- relates to the of inserted to maintain simple rapid handling gaps alignment. can tection of recombinant more mosaic se- The RIP either that are con- (or sequences broadly, "squeeze" gaps, meaning gaps and its to the env and se- sidered in where the and all con- gag positions quences), application coding except query subtype in the HIV Database.4 sensus are TI - A Computer Program Designed to Screen Rapidly for HIV Type 1 Intersubtype Recombinant Sequences JF - AIDS Research and Human Retroviruses DO - 10.1089/aid.1995.11.1413 DA - 1995-11-01 UR - https://www.deepdyve.com/lp/unpaywall/a-computer-program-designed-to-screen-rapidly-for-hiv-type-1-d4VxrxbF0A DP - DeepDyve ER -