TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 279, No. 19, Issue of May 7, pp. 20167–20177, 2004 © 2004 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. Identification of Transcription Factor Binding Sites Upstream of Human Genes Regulated by the Phosphatidylinositol 3-Kinase □ S and MEK/ERK Signaling Pathways* Received for publication, August 20, 2003, and in revised form, February 2, 2004 Published, JBC Papers in Press, February 9, 2004, DOI 10.1074/jbc.M309260200 ¶ ¶ John W. Tullai‡§, Michael E. Schaffer§ , Steven Mullenbrock‡, Simon Kasif , and Geoffrey M. Cooper‡ ** From the ‡Department of Biology, Bioinformatics Program, and the Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215 systems biology. However, computational identification of tran- We have taken an integrated approach in which ex- pression profiling has been combined with the use of scription factor binding sites is difficult because they consist of small molecule inhibitors and computational analysis of short, degenerate sequences that occur frequently by chance transcription factor binding sites to characterize regu- (1– 4). One approach to this problem is to search for genes that latory sequences of genes that are targets of specific share clusters of transcription factor binding sites, for 
TI - Identification of Transcription Factor Binding Sites Upstream of Human Genes Regulated by the Phosphatidylinositol 3-Kinase and MEK/ERK Signaling Pathways
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.m309260200
DA - 2004-05-01
UR - https://www.deepdyve.com/lp/unpaywall/identification-of-transcription-factor-binding-sites-upstream-of-human-dg2829cX02
DP - DeepDyve
ER -