TY - JOUR AU1 - Breitkreutz, Bobby-Joe AU2 - Stark, Chris AU3 - Reguly, Teresa AU4 - Boucher, Lorrie AU5 - Breitkreutz, Ashton AU6 - Livstone, Michael AU7 - Oughtred, Rose AU8 - Lackner, Daniel H. AU9 - Bähler, Jürg AU1 - Wood, Valerie AU1 - Dolinski, Kara AU1 - Tyers, Mike AB - The Biological General Repository for Interaction Datasets (BioGRID) database (http://www.thebiogrid.org) was developed to house and distribute collections of protein and genetic interactions from major model organism species. BioGRID currently contains over 198 000 interactions from six different species, as derived from both high-throughput studies and conventional focused studies. Through comprehensive curation efforts, BioGRID now includes a virtually complete set of interactions reported to date in the primary literature for both the budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe. A number of new features have been added to the BioGRID including an improved user interface to display interactions based on different attributes, a mirror site and a dedicated interaction management system to coordinate curation across different locations. The BioGRID provides interaction data with monthly updates to Saccharomyces Genome Database, Flybase and Entrez Gene. Source code for the BioGRID and the linked Osprey network visualization system is now freely available without restriction. TI - The BioGRID Interaction Database: 2008 update JF - Nucleic Acids Research DO - 10.1093/nar/gkm1001 DA - 2008-01-13 UR - https://www.deepdyve.com/lp/oxford-university-press/the-biogrid-interaction-database-2008-update-fnEhTEZIRL SP - D637 EP - D640 VL - 36 IS - suppl_1 DP - DeepDyve ER -