TY - JOUR AU - AB - Journal of 1Mathivanan, J Proteomics Bioinform 2012, 5:11 DOI: 10.4172/jpb.10000e16 ISSN: 0974-276X Proteomics & Bioinformatics Research Ar ticle Open Access Editorial Open Access Quest for Cancer Biomarkers: Assaying Mutant Proteins and RNA That Provides the Much Needed Specificity Suresh Mathivanan* Department of Biochemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia Cancer is the leading cause of death worldwide [1]. In 2008, it was of the ER and Golgi [20]. Currently, at least five non-classical secretory mechanisms are characterized i, exosomes ii, shedding microvesicles estimated that almost 12.7 million new cancer cases were diagnosed iii, ectodomain shedding iv, membrane transport channels, and v, flip and 7.6 million cancer deaths occurred worldwide [1,2]. Cancers of flop. lung, colon, breast, liver and prostate alone account for almost half of all the deaths [1,2]. Despite advances in surgical procedures, diagnostic Exosomes are 40-100 diameter membranous nanovesicles that are and therapeutic monitoring technologies, the patient survival rate released into the microenvironment upon fusion of the multivesicular is poor for most cancers [3]. Early diagnosis of cancer can increase bodies (MVBs) with the PM [21]. They are involved in intercellular patient survival rate [4] and is the most promising TI - Quest for Cancer Biomarkers: Assaying Mutant Proteins and RNA that Provides the Much Needed Specificity JO - Journal of Proteomics & Bioinformatics DO - 10.4172/jpb.10000e16 DA - 2012-01-01 UR - https://www.deepdyve.com/lp/unpaywall/quest-for-cancer-biomarkers-assaying-mutant-proteins-and-rna-that-fuuQHxf9G0 DP - DeepDyve ER -