TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 277, No. 41, Issue of October 11, pp. 38635–38646, 2002 © 2002 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. Receptor for Advanced Glycation End Products (RAGE) Signaling Induces CREB-dependent Chromogranin Expression during Neuronal Differentiation* Received for publication, March 15, 2002, and in revised form, August 6, 2002 Published, JBC Papers in Press, August 7, 2002, DOI 10.1074/jbc.M202515200 Henri J. Huttunen‡, Juha Kuja-Panula, and Heikki Rauvala From the Programme of Molecular Neurobiology, Institute of Biotechnology and the Department of Biosciences, University of Helsinki, Helsinki FIN-00014, Finland Receptor for advanced glycation end products cellular responses varying from cytokine secretion and in- (RAGE) mediates neurite outgrowth and cell migration creased cellular oxidant stress to neurite outgrowth and cell upon stimulation with its ligand, amphoterin. We show migration (for recent reviews, see Refs. 2– 4). Many of these here that RAGE-dependent changes in cell morphology responses are dependent of RAGE-mediated signal transduc- are associated with proliferation arrest and changes in tion and altered gene expression. Ligation of RAGE has been gene expression in neuroblastoma cells. Chromogranin shown to activate multiple signaling pathways, including Ras- B, a component of secretory vesicles in 
TI - Receptor for Advanced Glycation End Products (RAGE) Signaling Induces CREB-dependent Chromogranin Expression during Neuronal Differentiation
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.m202515200
DA - 2002-10-01
UR - https://www.deepdyve.com/lp/unpaywall/receptor-for-advanced-glycation-end-products-rage-signaling-induces-fw0Yt00nTv
DP - DeepDyve
ER -