TY - JOUR AU - Peiris, J. S. Malik AB - 5. The Severe Acute Respiratory Syndrome KWOK-YUNG YUEN, SAMSON S.Y. WONG, AND J.S. MALIK PEIRIS 5.1. Introduction Severe acute respiratory syndrome (SARS) was the f irst major pan- demic of the new millennium. It had dramatic impact on the health care systems, economies, and societies of countries directly affected. Since its emergence in 2002–2003, much has been learned about the disease and the causative agent, and this chapter summarizes the current understand- ing of the SARS coronavirus and the disease it causes. 5.2. Sequence of Events In the past century, Southern China has been the epicenter for emer- gence of some notable infectious diseases. The Hong Kong Special Administrative Region (HKSAR), being part of southern China, which has enjoyed a relatively more advanced public health infrastructure and international connectivity, often became the f irst place where such emerg- ing infectious diseases were discovered and from where they dissemi- nated globally. The f irst such example occurred in 1894 when an outbreak of plague started in Canton (now the Guangdong Province) of China. A similar outbreak, this time an acute community-acquired atypical pneu- monia syndrome, occurred in the Guangdong Province in late 2002. Retrospective investigations showed that severe cases of TI - The Severe Acute Respiratory Syndrome JF - New and Evolving Infections of the 21st Century DO - 10.1007/978-0-387-32830-0_5 DA - 2007-01-01 UR - https://www.deepdyve.com/lp/pubmed-central/the-severe-acute-respiratory-syndrome-klKssZ9A5J SP - 163 EP - 193 DP - DeepDyve ER -