TY - JOUR AU - Sugiyama, Yuichi AB - Pharmaceutical Research, Vol. 21, No. 11, November 2004 (© 2004) Letter to the Editor cific class or group of membrane transporter proteins, Transporter Database, TP-Search: whereas TP-Search aims at providing a comprehensive data- A Web-Accessible Comprehensive base on drug-transporters. Among those databases, the hu- man membrane transporter database has been intended to Database for Research in support pharmacogenomic studies and so provides much in- Pharmacokinetics of Drugs formation on sequence variants, altered functions caused by polymorphisms/mutations, and (patho)physiological role and This Letter to the Editor informs the readers of TP- associated diseases (5). The ADME-associated protein data- Search, a unique comprehensive database for membrane base provides comprehensive information on ADME- transporter proteins that we have constructed to facilitate the associated proteins, which include not only membrane trans- study of drug transporters on a broad scale in the world and porter proteins involved in drug disposition, but also other to provide a research tool for optimization of pharmacokinet- proteins, such as plasma proteins, intracellular binding pro- ic properties in terms of transporters during the early stage of teins, and drug metabolizing enzymes (6). Other transporter drug development in pharmaceutical companies. databases listed above are mainly focused on the information During TI - Transporter Database, TP-Search: A Web-Accessible Comprehensive Database for Research in Pharmacokinetics of Drugs JF - Pharmaceutical Research DO - 10.1023/B:PHAM.0000048207.11160.d0 DA - 2004-12-14 UR - https://www.deepdyve.com/lp/springer-journals/transporter-database-tp-search-a-web-accessible-comprehensive-database-kzJ7fgQ8OW SP - 2133 EP - 2134 VL - 21 IS - 11 DP - DeepDyve ER -