TY - JOUR AU - Ned S, Wingreen AB - Shifting the perspective of the questions we ask will ensure that network theory continues to excite the network theorists, but more importantly, that it remains vital to progress in biological research. The study of networks has expanded rapidly over the last 10 years; networks are now widely recognized not only as outcomes of complex interactions, but as key determinants of structure, function, and dynamics in systems that span the biological, physical, and social sciences [ 1–4 ]. The “new science of networks” [ 5 ] has introduced novel paradigms of systems behavior, including small-world structure [ 6 ], scale-free networks [ 7 ], and the importance of modularity [ 8 ] and motifs [ 9 ]. Some of these ideas have been transplanted into biology, and the results thus far are mixed but promising. Certainly, the study of biological networks has brought new opportunities for publication, yet much effort has been placed at discovering particular patterns in unexpected places—e.g., scale-free distributions in gene regulatory networks [ 10 ]—and these findings come with the caveat that similar patterns do not necessarily point to a common mechanistic origin [ 11 ]. Despite the many findings of power laws and hubs TI - Evolution, Interactions, and Biological Networks JF - PLoS Biology DO - 10.1371/journal.pbio.0050011 DA - 2007-01-16 UR - https://www.deepdyve.com/lp/public-library-of-science-plos-journal/evolution-interactions-and-biological-networks-l0obhPan8y VL - 5 IS - 1 DP - DeepDyve ER -