TY - JOUR AU - on behalf of the Asia Pacific HIV Observational Database, (APHOD) AB - Downloaded from http://journals.lww.com/jaids by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/12/2020 EPIDEMIOLOGY AND SOCIAL SCIENCE Long-Term Patterns in CD4 Response Are Determined by an Interaction Between Baseline CD4 Cell Count, Viral Load, and Time: The Asia Pacific HIV Observational Database (APHOD) Sam Egger, BSc, Mbiostat,* Kathy Petoumenos, PhD,† Adeeba Kamarulzaman, MBBS, FRACP,‡ Jennifer Hoy, MBBS, FRACP,§ Somnuek Sungkanuparph, MD, John Chuah, MBBS, BSc(Med), Hons FAchSHM,¶ Kathleen Falster, BAppSc(Hons), MPH,†# Jialun Zhou, BMed, MPH, PhD,† and Matthew G. Law, MA, MSc, PhD† on behalf of the Asia Pacific HIV Observational Database (APHOD) Results: A total of 1638 patients fulfilled the inclusion criteria with Background: Random effects models were used to explore how the a median follow-up time of 58 months. Lower post-cART mean CD4 shape of CD4 cell count responses after commencing combination cell counts were found to be associated with increasing age (P , antiretroviral therapy (cART) develop over time and, in particular, the 0.001), pre-cART hepatitis C coinfection (P = 0.038), prior AIDS role of baseline and follow-up covariates. (P = 0.019), baseline viral load #100,000 copies per milliliter (P , 0.001), and the Asia Pacific region compared with Australia (P = Methods: Patients in Asia Pacific HIV Observational Database who 0.005). TI - Long-Term Patterns in CD4 Response Are Determined by an Interaction Between Baseline CD4 Cell Count, Viral Load, and Time: The Asia Pacific HIV Observational Database (APHOD) JF - JAIDS Journal of Acquired Immune Deficiency Syndromes DO - 10.1097/QAI.0b013e31819906d3 DA - 2009-04-01 UR - https://www.deepdyve.com/lp/wolters-kluwer-health/long-term-patterns-in-cd4-response-are-determined-by-an-interaction-lbogNoq07Z SP - 513 VL - 50 IS - 5 DP - DeepDyve ER -