TY - JOUR AU1 - Kango-Singh, Madhuri AB - BOOK REVIEW of the human genome sequence and variation. The chapter on chromosomes elegantly links the classical Book Review ideas and techniques of cytogenetic analysis to the modern techniques of detecting karyotypic abnormal- ities (structural or numerical) associated with human chromosomes (like fibre-fluorescence in situ hybridis- Vogel and Motulsky’s Human ation [FISH]- and array-based methods). Another Genetics — Problems and chapter describes the currently popular high-throughput Approaches ‘omics’ approaches. The next five chapters are dedicated to introducing the Michael Speicher, Stylianos E. Antonarakis, Arno reader to Mendelian genetics as applied to the inheritance G. Motulsky (eds) of genetic traits in humans. This includes everything from Springer; 4th edn; 2010; LIV; 981 pp. 343 illus- modes of inheritance to concepts of linkage and their trations (160 in colour); Hardback; ISBN: 978-3- implications for inheritance, monogenic versus oligogenic 540-37653-8; US$199.00 traits, multifactorial diseases in humans and findings from genome-wide association studies. Epigenetics has garnered a lot of attention recently, Human genetics is a vast and fascinating field that is and this edition includes chapters dedicated to the evolving rapidly with the advent of new techniques in effects of chromatin remodelling, imprinting, etc. on molecular biology and genomics. In its fourth incarna- TI - Vogel and Motulsky's human genetics-problems and approaches: Michael Speicher, Stylianos E. Antonarakis, Arno G. Motulsky (eds) JF - Human Genomics DO - 10.1186/1479-7364-5-1-73 DA - 2010-10-01 UR - https://www.deepdyve.com/lp/springer-journals/vogel-and-motulsky-s-human-genetics-problems-and-approaches-michael-lnlMG4bptu SP - 1 EP - 2 VL - 5 IS - 1 DP - DeepDyve ER -