TY - JOUR
AU - Hovig, Eivind
AB - Summary: Recently developed methods that couple next-generation sequencing with chromosome conformation capture-based techniques, such as Hi-C and ChIA-PET, allow for characterization of genome-wide chromatin 3D structure. Understanding the organization of chromatin in three dimensions is a crucial next step in the unraveling of global gene regulation, and methods for analyzing such data are needed. We have developed HiBrowse, a user-friendly web-tool consisting of a range of hypothesis-based and descriptive statistics, using realistic assumptions in null-models.Availability and implementation: HiBrowse is supported by all major browsers, and is freely available at http://hyperbrowser.uio.no/3d. Software is implemented in Python, and source code is available for download by following instructions on the main site.Contact:
jonaspau@ifi.uio.noSupplementary Information:
Supplementary data are available at Bioinformatics online.
TI - HiBrowse: multi-purpose statistical analysis of genome-wide chromatin 3D organization
JF - Bioinformatics
DO - 10.1093/bioinformatics/btu082
DA - 2014-02-07
UR - https://www.deepdyve.com/lp/pubmed-central/hibrowse-multi-purpose-statistical-analysis-of-genome-wide-chromatin-lzcNZAsRfP
SP - 1620
EP - 1622
VL - 30
IS - 11
DP - DeepDyve
ER -