TY - JOUR
AU - Cuppen, Edwin
AB - Background: With the recent progress made in large-scale genome sequencing projects a vast amount of novel data is becoming available. A comparative sequence analysis, exploiting sequence information from various resources, can be used to uncover hidden information, such as genetic variation. Although there are enormous amounts of SNPs for a wide variety of organisms submitted to NCBI dbSNP and annotated in most genome assembly viewers like Ensembl and the UCSC Genome Browser, these platforms do not easily allow for extensive annotation and incorporation of experimental data supporting the polymorphism. However, such information is very important for selecting the most promising and useful candidate polymorphisms for use in experimental setups. Description: The CASCAD database is designed for presentation and query of candidate SNPs that are retrieved by in silico mining of high-throughput sequencing data. Currently, the database provides collections of laboratory rat (Rattus norvegicus) and zebrafish (Danio rerio) candidate SNPs. The database stores detailed information about raw data supporting the candidate, extensive annotation and links to external databases (e.g. GenBank, Ensembl, UniGene, and LocusLink), verification information, and predictions of a potential effect for non-synonymous polymorphisms in coding regions. The CASCAD website allows search based on an arbitrary combination of 27 
TI - CASCAD: a database of annotated candidate single nucleotide polymorphisms associated with expressed sequences
JF - BMC Genomics
DO - 10.1186/1471-2164-6-10
DA - 2005-01-27
UR - https://www.deepdyve.com/lp/springer-journals/cascad-a-database-of-annotated-candidate-single-nucleotide-mmC0Y8byhN
SP - 1
EP - 4
VL - 6
IS - 1
DP - DeepDyve
ER -