TY - JOUR AU1 - Ebrahimpour-Koujan, Soraiya AU2 - Sohrabpour, Amir Ali AU3 - Safari, Saeid AU4 - Baziar, Nima AU5 - Hadavi, Shima AU6 - Payahoo, Laleh AU7 - Shabani, Samaneh AB - Coronavirus disease-2019 (COVID-19) is becoming a crucial health problem worldwide. Continued and high-speed mutations of this virus result in the appearance of new manifestations, making the control of this disease difficult. It has been shown that well-nourished patients have strong immune systems who mostly have short-term hospitalization compared to others. The purpose of this study is to review the major nutrients involved in the immune system reinforcement and to explain nutritional aspects during the recovery of COVID-19.Design/methodology/approachIn this review paper, the mechanistic role of nutrients in boosting the immune system and the nutritional aspects during the recovery of COVID-19 patients were discussed. Papers indexed in scientific databases were searched using antioxidants, COVID-19, inflammation, immune system, macronutrient, micronutrient and probiotic as keywords from 2000 to 2022.FindingsBecause of the adverse effects of drugs like thrombosis, pulmonary embolism and hypercholesterolemia, a balanced diet with enough concentrations of energy and macronutrients could increase the patient's durability. The inflammatory cytokines in a vicious cycle delay patients’ rehabilitation. The main mechanistic roles of micronutrients are attributed to the downregulation of virus replication and are involved in energy homeostasis. Dysbiosis is defined as another disturbance among COVID-19 patients, and supplementation with beneficial strains of probiotics helps to exert anti-inflammatory effects in this regard. Being on a well-planned diet with anti-inflammatory properties could reverse cytokine storms as the major feature of COVID-19. Future studies are needed to determine the safe and effective dose of dietary factors to control the COVID-19 patients.Originality/valueBeing on a well-planned diet with anti-inflammatory properties could reverse cytokine storms as the major feature of COVID-19. Future studies are needed to determine the safe and effective dose of dietary factors to control the COVID-19 patients. TI - A comprehensive nutritional support perspective in patients with COVID-19: a review JF - Nutrition & Food Science DO - 10.1108/nfs-01-2022-0015 DA - 2023-02-07 UR - https://www.deepdyve.com/lp/emerald-publishing/a-comprehensive-nutritional-support-perspective-in-patients-with-covid-o18d3Mwwl7 SP - 334 EP - 357 VL - 53 IS - 2 DP - DeepDyve ER -