TY - JOUR
AU1 - Rodrigues, Luciano
AU2 - Ferreira, Deusmaque
AU3 - Ferreira, Lucas
AU4 - Cuadros-Orellana, Sara
AU5 - Oliveira, Guilherme
AU6 - Brito-Madurro, Ana
AU7 - Oliveira, Ronaldo
AU8 - Abrahão, Odonírio
AU9 - Madurro, João
AB - In this work, three polymeric films derived from hydroxyphenylacetic acid isomers were electropolymerized onto the surfaces of graphite electrodes through cyclic voltammetry. Analysis of electrochemical behaviors and electrical properties of the three polymeric films were investigated and their probably structures were explored by molecular modeling. The best functionalization strategy for the incorporation and retention of adenine and guanine nitrogenous bases was the poly(3-hydroxyphenylacetic acid). It was applied for the immobilization of a nucleotide probe specific to DNA of the bacteria Neisseria meningitidis operated in amperometric and impedimetric indirect modes. The simple protocol of electrochemical detection of DNA by the bioelectrode, developed in this work, could be further enhanced and applied in a low-cost and pain-less platform to diagnose human meningitis infection.
TI - Electropolymerization of hydroxyphenylacetic acid isomers and the development of a bioelectrode for the diagnosis of bacterial meningitis
JF - Journal of Applied Electrochemistry
DO - 10.1007/s10800-015-0892-2
DA - 2015-10-07
UR - https://www.deepdyve.com/lp/springer-journals/electropolymerization-of-hydroxyphenylacetic-acid-isomers-and-the-omtgXI7dRI
SP - 1277
EP - 1287
VL - 45
IS - 12
DP - DeepDyve
ER -