TY - JOUR
AU - Poole, A Robin
AB - Articular cartilage degeneration in osteoarthritis (OA) involves excessive degradation of extracellular matrix (ECM) and chondrocyte differentiation (hypertrophy). We determined the interrelationship between the extent of collagen cleavage by collagenase, cartilage degeneration, and differentiation related gene expression in patella-femoral condylar cartilages of patients bearing very early focal OA-like articular cartilage lesions.
TI - Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions.
JF - The Journal of rheumatology
DA - 2005-08-09
UR - https://www.deepdyve.com/lp/pubmed/increased-type-ii-collagen-degradation-and-very-early-focal-cartilage-ponrdmXWEM
SP - 876
EP - 886
VL - 32
IS - 5
DP - DeepDyve
ER -