TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 276, No. 27, Issue of July 6, pp. 24531–24539, 2001 © 2001 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. Differential Usage of Signal Transduction Pathways Defines Two Types of Serum Response Factor Target Gene* Received for publication, March 26, 2001, and in revised form, April 27, 2001 Published, JBC Papers in Press, May 7, 2001, DOI 10.1074/jbc.M102678200 Dziugas Gineitis‡ and Richard Treisman§ From the Transcription Laboratory, Imperial Cancer Research Fund Laboratories, 44 Lincoln’s Inn Fields, London WC2A 3PX, United Kingdom Activation of the transcription factor serum response forms a ternary complex with members of the ternary complex factor (TCF) family of mitogen-activated protein kinase-regu- factor (SRF) is dependent on Rho-controlled changes in actin dynamics. We used pathway-specific inhibitors to lated Ets domain proteins (Ref. 2; for review see Ref. 3). It compare the roles of actin dynamics, extracellular sig- remains unclear whether all SRF-controlled immediate-early nal-regulated kinase (ERK) signaling, and phosphatidy- gene promoters bind TCF, however, because the TCF recogni- linositol 3-kinase in signaling either to SRF itself or to tion site is simple and can be located at variable distances from four cellular SRF target genes. 
TI - Differential Usage of Signal Transduction Pathways Defines Two Types of Serum Response Factor Target Gene
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.m102678200
DA - 2001-01-01
UR - https://www.deepdyve.com/lp/unpaywall/differential-usage-of-signal-transduction-pathways-defines-two-types-puR7wG00Rw
DP - DeepDyve
ER -