TY - JOUR
AU - Jingye, Pan
AB - We investigated the extended-spectrum beta lactamases among 62 Salmonella enterica Typhimurium isolates recovered from children with diarrhea in a Chinese pediatric hospital. A large proportion of S. enterica Typhimurium isolates were resistant to multiple antimicrobial agents, including ampicillin (90.3%), tetracycline (80.6%), trimethoprim/sulfamethoxazole (74.2%), chloramphenicol (66.1%), cefotaxime (27.4%). Forty-nine (79.0%) of S. enterica Typhimurium isolates were positive for bla TEM-1b and resistant to ampicillin. Thirteen S. enterica Typhimurium isolates (21.0%) were positive for bla CTX-M-1-group and bla CTX-M-9-group , and all isolates harboring bla CTX-M genes were positive for IS Ecp1. Two main clones (PFGE type A and D) accounted for nearly 70% of S. enterica Typhimurium isolates, and 7 CTX-M-producing isolates belonged to PFGE type D. Collectively, our data reveal multi-drug resistance and a high prevalence of extended spectrum beta lactamases among S. enterica Typhimurium isolates from children in China. In addition, we report the first identification of bla CTX-M-55 within Salmonella spp . Our data also suggest that clonal spread is responsible for the dissemination of S. enterica Typhimurium isolates.
TI - High Prevalence of Extended-Spectrum Beta Lactamases among Salmonella enterica Typhimurium Isolates from Pediatric Patients with Diarrhea in China
JF - PLoS ONE
DO - 10.1371/journal.pone.0016801
DA - 2011-03-01
UR - https://www.deepdyve.com/lp/public-library-of-science-plos-journal/high-prevalence-of-extended-spectrum-beta-lactamases-among-salmonella-slsine3Vql
VL - 6
IS - 3
DP - DeepDyve
ER -