TY - JOUR
AU - Ahn, Chul
AB - Clinical investigators often find the thought of writing the statistical analysis plan daunting. Early collaboration between the clinical investigator and statistician can improve the study design and validity of the results by developing the statistical methodology that specifically addresses the research hypothesis. With the clinical investigator, a statistician often writes the statistical methods section that includes sample size and power analyses, randomization and blinding procedures, interim analysis, and data monitoring plans, in addition to the statistical analysis plan. To make this process less mysterious, we describe how the statistical methods section is developed in collaboration with a statistician.
TI - Bridging Clinical Investigators and Statisticians: Writing the Statistical Methodology for a Research Proposal
JF - Journal of Investigative Medicine
DO - 10.2310/jim.0b013e3181c2996c
DA - 2009-12-01
UR - https://www.deepdyve.com/lp/sage/bridging-clinical-investigators-and-statisticians-writing-the-tWbC0rNsOF
SP - 818
EP - 824
VL - 57
IS - 8
DP - DeepDyve
ER -