TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 273, No. 23, Issue of June 5, pp. 14484 –14494, 1998 © 1998 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. Amino Acid Sufficiency and mTOR Regulate p70 S6 Kinase and eIF-4E BP1 through a Common Effector Mechanism* (Received for publication, November 26, 1997, and in revised form, February 17, 1998) Kenta Hara‡§¶i, Kazuyoshi Yonezawa§¶, Qing-Ping Weng‡, Mark T. Kozlowski‡, Christopher Belham‡, and Joseph Avruch‡** From the ‡Diabetes Unit and Medical Services, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129 and the §Biosignal Research Center, Kobe University, Kobe 657, Japan The present study identifies the operation of a signal synthesis in skeletal muscle; however, much evidence indicates that a major portion of the increase in the skeletal muscle tranduction pathway in mammalian cells that provides a checkpoint control, linking amino acid sufficiency to protein synthesis in vivo seen on refeeding is independent of the control of peptide chain initiation. Withdrawal of changes in insulin and perhaps attributable to the nutrients amino acids from the nutrient medium of CHO-IR cells themselves (2). Nevertheless, in vivo it is difficult to isolate the results in a rapid deactivation of 
TI - Amino Acid Sufficiency and mTOR Regulate p70 S6 Kinase and eIF-4E BP1 through a Common Effector Mechanism
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.273.23.14484
DA - 1998-06-01
UR - https://www.deepdyve.com/lp/unpaywall/amino-acid-sufficiency-and-mtor-regulate-p70-s6-kinase-and-eif-4e-bp1-tvUD38FPk6
DP - DeepDyve
ER -