TY - JOUR
AU1 - Pagnotti, Vincent
AU2 - Chakrabarty, Shubhashis
AU3 - McEwen, Charles
AB - Solvent Assisted Ionization Inlet (SAII) produces ions in a heated inlet to a mass spectrometer from aqueous and aqueous/organic solutions with high sensitivity. However, the use of acid modifiers, which typically aids electrospray ionization, generally results in ion suppression in SAII. Here we demonstrate that the use of carbonation and other super-saturated gases as solution modifiers increases analyte ion abundance and reduces metal cation adduction in SAII. Carbonation is also found to enhance electrospray ionization. The mechanistic and practical utility of carbonation in mass spectrometry is addressed.
TI - Carbonation and Other Super Saturated Gases as Solution Modifiers for Improved Sensitivity in Solvent Assisted Ionization Inlet (SAII) and ESI
JF - Journal of the American Society for Mass Spectrometry
DO - 10.1007/s13361-012-0535-3
DA - 2013-01-08
UR - https://www.deepdyve.com/lp/springer-journals/carbonation-and-other-super-saturated-gases-as-solution-modifiers-for-u1JDl0ZbzV
SP - 186
EP - 192
VL - 24
IS - 2
DP - DeepDyve
ER -