TY - JOUR AU - Margaret Biswas, John F. O'Rourke, Evelyn Camon, Gill Fraser, Alexander Kanapin, Youla Karavidopoulou, Paul Kersey, Evgenia Kriventseva, Virginie Mittard, Nicola Mulder, Isabelle Phan, Florence Servant, Rolf Apweiler AB - The applications of InterPro span a range of biologically important areas that includes automatic annotation of protein sequences and genome analysis. In automatic annotation of protein sequences InterPro has been utilised to provide reliable characterisation of sequences, identifying them as candidates for functional annotation. Rules based on the InterPro characterisation are stored and operated through a database called RuleBase. RuleBase is used as the main tool in the sequence database group at the EBI to apply automatic annotation to unknown sequences. The annotated sequences are stored and distributed in the TrEMBL protein sequence database. InterPro also provides a means to carry out statistical and comparative analyses of whole genomes. In the Proteome Analysis Database, InterPro analyses have been combined with other analyses based on CluSTr, the Gene Ontology (GO) and structural information on the proteins. Key words automatic annotation genome comparison protein classification functional annotation proteome comparison © Henry Stewart Publications « Previous | Next Article » Table of Contents This Article Brief Bioinform (2002) 3 (3): 285-295. doi: 10.1093/bib/3.3.285 This article appears in: InterPro » Abstract Free Full Text (PDF) Free Classifications Paper Services Article metrics Alert me when cited Alert me if corrected Find similar articles Similar articles in Web of Science Similar articles in PubMed Add to my archive Download citation Request Permissions Citing Articles Load citing article information Citing articles via CrossRef Citing articles via Scopus Citing articles via Web of Science Citing articles via Google Scholar Google Scholar Articles by Biswas, M. Articles by Apweiler, R. 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