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- Copyright
- ©2010 American Academy of Child and Adolescent Psychiatry
- ISSN
- 0890-8567
- DOI
- 10.1016/j.jaac.2010.06.007
- pmid
- 20732627
- Publisher site
- See Article on Publisher Site
Abstract
NEW RESEARCH Case-Control Genome-Wide Association Study of Attention- Deficit/Hyperactivity Disorder Benjamin M. Neale, Ph.D., Sarah Medland, Ph.D., Stephan Ripke, M.D., Richard J.L. Anney, Ph.D., Philip Asherson, M.R.C.Psych., Ph.D., Jan Buitelaar, M.D., Barbara Franke, Ph.D., Michael Gill, M.B., Bch, BAO, M.D., MRCPsych, F.T.C.D., Lindsey Kent, M.D., Ph.D., Peter Holmans, Ph.D., Frank Middleton, Ph.D., Anita Thapar, M.D., Klaus-Peter Lesch, M.D., Stephen V. Faraone, Ph.D., Mark Daly, Ph.D., Thuy Trang Nguyen, Dipl. Math. oec, Helmut Schäfer, Ph.D., Hans-Christoph Steinhausen, M.D., Ph.D., D.M.Sc., Andreas Reif, M.D., Tobias J. Renner, M.D., Marcel Romanos, M.D., Jasmin Romanos, M.D., Andreas Warnke, M.D., Ph.D., Susanne Walitza, M.D., Christine Freitag, M.D., M.A., Jobst Meyer, Ph.D., Haukur Palmason, Ph.D., Aribert Rothenberger, M.D., Ph.D., Ziarih Hawi, Joseph Sergeant, Ph.D., Herbert Roeyers, M.D., Ph.D., Eric Mick, Sc.D., Joseph Biederman, M.D., for the IMAGE II Consortium Objective: Although twin and family studies have shown attention-deficit/hyperactivity disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome- wide significant level have yet to be identified. Thus additional genomewide association studies (GWAS) are needed. Method: We used case-control analyses of 896 cases with DSM-IV ADHD genotyped using the Affymetrix 5.0 array and 2,455 repository controls screened for psychotic and bipolar symptoms
Journal
Journal of the American Academy of Child & Adolescent Psychiatry – Wolters Kluwer Health
Published: Sep 1, 2010