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Spleen Stiffness in Patients With Cirrhosis in Predicting Esophageal Varices

Spleen Stiffness in Patients With Cirrhosis in Predicting Esophageal Varices Downloaded from http://journals.lww.com/ajg by BhDMf5ePHKbH4TTImqenVJ2toCr/9wZZjwPUWvYES9lBjFbu9i0DAnSw4JagSjiU on 10/29/2020 nature publishing group ORIGINAL CONTRIBUTIONS 1101 see related editorial on page x Spleen Stiffness in Patients With Cirrhosis in Predicting Esophageal Varices 1 1 1 1 1 Praveen Sharma , MD, DM , Vijender Kirnake , MD , Pankaj Tyagi , MD, DM , Naresh Bansal , MD, DNB , Vikas Singla , MD, DM , 1 1 Ashish Kumar , MD, DM and Anil Arora , MD, DM OBJECTIVES: Screening for esophageal varices (EV) is recommended in patients with cirrhosis. Noninvasive tests had shown varying sensitivity (Se) and specifi city (Sp) for predicting EV. Splenomegaly is a common fi nding in liver cirrhosis because of portal and splenic congestion. These changes can be quantifi ed by transient elastography; hence, the aim of this study was to investigate the utility of spleen stiffness (SS) in evaluating EV in comparison with other noninvasive tests. METHODS: We measured SS and liver stiffness (LS) by using FibroScan in 200 consecutive cirrhotic patients who met the inclusion criteria. Patients were also assessed by hepatic venous pressure gradient (HVPG), upper gastrointestinal endoscopy, LS – spleen diameter to platelet ratio score (LSPS), and platelet count to spleen diameter http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Gastroenterology Wolters Kluwer Health

Spleen Stiffness in Patients With Cirrhosis in Predicting Esophageal Varices

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Publisher
Wolters Kluwer Health
Copyright
© The American College of Gastroenterology 2013. All Rights Reserved.
ISSN
0002-9270
eISSN
1572-0241
DOI
10.1038/ajg.2013.119
Publisher site
See Article on Publisher Site

Abstract

Downloaded from http://journals.lww.com/ajg by BhDMf5ePHKbH4TTImqenVJ2toCr/9wZZjwPUWvYES9lBjFbu9i0DAnSw4JagSjiU on 10/29/2020 nature publishing group ORIGINAL CONTRIBUTIONS 1101 see related editorial on page x Spleen Stiffness in Patients With Cirrhosis in Predicting Esophageal Varices 1 1 1 1 1 Praveen Sharma , MD, DM , Vijender Kirnake , MD , Pankaj Tyagi , MD, DM , Naresh Bansal , MD, DNB , Vikas Singla , MD, DM , 1 1 Ashish Kumar , MD, DM and Anil Arora , MD, DM OBJECTIVES: Screening for esophageal varices (EV) is recommended in patients with cirrhosis. Noninvasive tests had shown varying sensitivity (Se) and specifi city (Sp) for predicting EV. Splenomegaly is a common fi nding in liver cirrhosis because of portal and splenic congestion. These changes can be quantifi ed by transient elastography; hence, the aim of this study was to investigate the utility of spleen stiffness (SS) in evaluating EV in comparison with other noninvasive tests. METHODS: We measured SS and liver stiffness (LS) by using FibroScan in 200 consecutive cirrhotic patients who met the inclusion criteria. Patients were also assessed by hepatic venous pressure gradient (HVPG), upper gastrointestinal endoscopy, LS – spleen diameter to platelet ratio score (LSPS), and platelet count to spleen diameter

Journal

American Journal of Gastroenterology – Wolters Kluwer Health

Published: Jul 1, 2013

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