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How microorganisms tip the balance between interleukin-12 family members

How microorganisms tip the balance between interleukin-12 family members Distinct members of the interleukin-12 (IL-12) cytokine family can differentially regulate T-cell-mediated inflammation. In this Opinion article, the authors propose that microbial products and endogenous mediators can control the balance between these cytokines, thereby directly regulating the inflammatory response. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Reviews Immunology Springer Journals

How microorganisms tip the balance between interleukin-12 family members

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References (74)

Publisher
Springer Journals
Copyright
Copyright © 2008 by Nature Publishing Group
Subject
Biomedicine; Biomedicine, general; Immunology
ISSN
1474-1733
eISSN
1474-1741
DOI
10.1038/nri2225
Publisher site
See Article on Publisher Site

Abstract

Distinct members of the interleukin-12 (IL-12) cytokine family can differentially regulate T-cell-mediated inflammation. In this Opinion article, the authors propose that microbial products and endogenous mediators can control the balance between these cytokines, thereby directly regulating the inflammatory response.

Journal

Nature Reviews ImmunologySpringer Journals

Published: Jan 1, 2008

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