/lp/springer-journals/opposing-regulation-of-the-locus-encoding-il-17-through-direct-0rxc3NHFyb
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- Publisher
- Springer Journals
- Copyright
- Copyright © 2011 by Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.
- Subject
- Biomedicine; Biomedicine, general; Immunology; Infectious Diseases
- ISSN
- 1529-2908
- eISSN
- 1529-2916
- DOI
- 10.1038/ni.1995
- Publisher site
- See Article on Publisher Site
Abstract
Loss of IL-2 signaling results in autoimmunity. Laurence and colleagues show that the IL-2–STAT5 axis counteracts STAT3 activation of Il17 to dampen IL-17 production independently of Foxp3.
Journal
Nature Immunology – Springer Journals
Published: Jan 30, 2011