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Coffee prevents CCl4-induced liver cirrhosis in the rat

Coffee prevents CCl4-induced liver cirrhosis in the rat Hepatol Int (2011) 5:857–863 DOI 10.1007/s12072-010-9247-6 O R I G IN AL ARTI CL E Coffee prevents CCl -induced liver cirrhosis in the rat • • • Mario G. Moreno Enrique Cha ´ vez Liseth R. Aldaba-Muruato • • • • Jose ´ Segovia Paula Vergara Vı ´ctor Tsutsumi Mineko Shibayama Yadira Rivera-Espinoza Pablo Muriel Received: 15 June 2010 / Accepted: 29 December 2010 / Published online: 25 January 2011 Asian Pacific Association for the Study of the Liver 2011 Abstract analysis was in agreement with biochemical and molecular Purpose Previous clinical observations suggested that data. The best effect was produced by GC. It is worth coffee may have beneficial effects on the liver. In fact, an noting that GC preserved the normal collagen content as inverse relationship between coffee consumption and liver well as the normal TGF-b mRNA and protein levels. cirrhosis has been reported in humans. However, the Conclusions Our results suggest (1) that coffee plays a causative role of coffee has not been established; therefore, causative role in preventing cirrhosis (at least experimental the aim of this work was to study the effect of coffee in an cirrhosis); (2) that action mechanisms are probably asso- experimental http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Hepatology International Springer Journals

Coffee prevents CCl4-induced liver cirrhosis in the rat

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References (42)

Publisher
Springer Journals
Copyright
Copyright © 2011 by Asian Pacific Association for the Study of the Liver
Subject
Medicine & Public Health; Surgery; Hepatology; Colorectal Surgery
ISSN
1936-0533
eISSN
1936-0541
DOI
10.1007/s12072-010-9247-6
pmid
21484136
Publisher site
See Article on Publisher Site

Abstract

Hepatol Int (2011) 5:857–863 DOI 10.1007/s12072-010-9247-6 O R I G IN AL ARTI CL E Coffee prevents CCl -induced liver cirrhosis in the rat • • • Mario G. Moreno Enrique Cha ´ vez Liseth R. Aldaba-Muruato • • • • Jose ´ Segovia Paula Vergara Vı ´ctor Tsutsumi Mineko Shibayama Yadira Rivera-Espinoza Pablo Muriel Received: 15 June 2010 / Accepted: 29 December 2010 / Published online: 25 January 2011 Asian Pacific Association for the Study of the Liver 2011 Abstract analysis was in agreement with biochemical and molecular Purpose Previous clinical observations suggested that data. The best effect was produced by GC. It is worth coffee may have beneficial effects on the liver. In fact, an noting that GC preserved the normal collagen content as inverse relationship between coffee consumption and liver well as the normal TGF-b mRNA and protein levels. cirrhosis has been reported in humans. However, the Conclusions Our results suggest (1) that coffee plays a causative role of coffee has not been established; therefore, causative role in preventing cirrhosis (at least experimental the aim of this work was to study the effect of coffee in an cirrhosis); (2) that action mechanisms are probably asso- experimental

Journal

Hepatology International – Springer Journals

Published: Jan 25, 2011

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