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More About: Tumor Angiogenesis as a Prognostic Assay for Invasive Ductal Breast Carcinoma

More About: Tumor Angiogenesis as a Prognostic Assay for Invasive Ductal Breast Carcinoma Table 1. Concordance of tumor angiogenesis counts* MVD (BL) MVD (KA) CORRESPONDENCE A) Pearson correlation analysis among counts for individual slides MVD (KA) 0.471 Chalkley count 0.349 0.386 B) Kappa analysis for classification of slides into tertiles† More About: Tumor MVD (KA) 0.27 Angiogenesis as a Prognostic Chalkley count 0.27 0.24 Assay for Invasive Ductal Breast Carcinoma *Microvessels in tumors from 169 patients with breast cancer were stained immunocytochemically with an antibody against factor VIII. Microvessel density (MVD) was measured by two observers. Indepen- dently, they scanned each slide under low power (×25 or ×100) and selected the three apparently most Axelsson et al. (1) reported in this vascular regions in each slide. Each observer (B.-M. Ljung and K. Axelsson), counted the total number 2 2 Journal that microvessel density (MVD) of microvessels in three high-power fields (×250; 0.32 mm or 0.37 mm , respectively), one from each region (1). For the present study, each slide then was counted by a third independent observer who also in 220 breast cancers did not provide selected the three apparently most vascular regions but who used a 25-point Chalkley eyepiece graticule prognostic information for metastasis- to assist in counting (4). The graticule http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JNCI Journal of the National Cancer Institute Oxford University Press

More About: Tumor Angiogenesis as a Prognostic Assay for Invasive Ductal Breast Carcinoma

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Publisher
Oxford University Press
Copyright
Oxford University Press
ISSN
0027-8874
eISSN
1460-2105
DOI
10.1093/jnci/92.2.161
Publisher site
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Abstract

Table 1. Concordance of tumor angiogenesis counts* MVD (BL) MVD (KA) CORRESPONDENCE A) Pearson correlation analysis among counts for individual slides MVD (KA) 0.471 Chalkley count 0.349 0.386 B) Kappa analysis for classification of slides into tertiles† More About: Tumor MVD (KA) 0.27 Angiogenesis as a Prognostic Chalkley count 0.27 0.24 Assay for Invasive Ductal Breast Carcinoma *Microvessels in tumors from 169 patients with breast cancer were stained immunocytochemically with an antibody against factor VIII. Microvessel density (MVD) was measured by two observers. Indepen- dently, they scanned each slide under low power (×25 or ×100) and selected the three apparently most Axelsson et al. (1) reported in this vascular regions in each slide. Each observer (B.-M. Ljung and K. Axelsson), counted the total number 2 2 Journal that microvessel density (MVD) of microvessels in three high-power fields (×250; 0.32 mm or 0.37 mm , respectively), one from each region (1). For the present study, each slide then was counted by a third independent observer who also in 220 breast cancers did not provide selected the three apparently most vascular regions but who used a 25-point Chalkley eyepiece graticule prognostic information for metastasis- to assist in counting (4). The graticule

Journal

JNCI Journal of the National Cancer Institute – Oxford University Press

Published: Jan 19, 2000

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