Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Direct observation of kinesin stepping by optical trapping interferometry

Direct observation of kinesin stepping by optical trapping interferometry Do biological motors move with regular steps? To address this question, we constructed instrumentation with the spatial and temporal sensitivity to resolve movement on a molecular scale. We deposited silica beads carrying single molecules of the motor protein kinesin on microtubules using optical tweezers and analysed their motion under controlled loads by interferometry. We find that kinesin moves with 8-nm steps. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Springer Journals

Direct observation of kinesin stepping by optical trapping interferometry

Loading next page...
 
/lp/springer-journals/direct-observation-of-kinesin-stepping-by-optical-trapping-5EeXRNSvCQ

References (46)

Publisher
Springer Journals
Copyright
Copyright © 1993 by Nature Publishing Group
Subject
Science, Humanities and Social Sciences, multidisciplinary; Science, Humanities and Social Sciences, multidisciplinary; Science, multidisciplinary
ISSN
0028-0836
eISSN
1476-4687
DOI
10.1038/365721a0
Publisher site
See Article on Publisher Site

Abstract

Do biological motors move with regular steps? To address this question, we constructed instrumentation with the spatial and temporal sensitivity to resolve movement on a molecular scale. We deposited silica beads carrying single molecules of the motor protein kinesin on microtubules using optical tweezers and analysed their motion under controlled loads by interferometry. We find that kinesin moves with 8-nm steps.

Journal

NatureSpringer Journals

Published: Oct 21, 1993

There are no references for this article.