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THE AETIOLOGY OF ANENCEPHALY

THE AETIOLOGY OF ANENCEPHALY INTRODUCTION THEobvious approach to the problem of foetal malformations is the initial determination of their incidence in various groups of patients. Perhaps the most defined malformation and the one least likely to be overlooked is anencephaly. The present paper is devoted to a study of the incidence of this abnormality alone without associated deformities. Similar enquiries have been carried out by Malpas (1937), whose material was derived entirely from the Liverpool Maternity Hospital, and by Record and McKeown (1949) who drew their material from the total births in Birmingham over a given period. This material was drawn from several sources whose population was known and in which the complete records of anencephalic births were available. RESULTS Isle of Man. This is mainly a rural area with a virtually closed population which is largely homogeneous. Most of the births took place in hospital and the records are complete from about 1935 to 1950. The general incidence of anencephaly was 0.11 per 1,000 births. Wrexham. This is a mixed industrial and agricultural area with a heterogeneous population. The incidence was 0.11 per 1,000 births. Billinge. This is a self-contained coal-mining area and the incidence was 0.22 per 1,000 births. St. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png BJOG : An International Journal of Obstetrics & Gynaecology Wiley

THE AETIOLOGY OF ANENCEPHALY

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References (2)

Publisher
Wiley
Copyright
Copyright © 1953 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1470-0328
eISSN
1471-0528
DOI
10.1111/j.1471-0528.1953.tb07296.x
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTION THEobvious approach to the problem of foetal malformations is the initial determination of their incidence in various groups of patients. Perhaps the most defined malformation and the one least likely to be overlooked is anencephaly. The present paper is devoted to a study of the incidence of this abnormality alone without associated deformities. Similar enquiries have been carried out by Malpas (1937), whose material was derived entirely from the Liverpool Maternity Hospital, and by Record and McKeown (1949) who drew their material from the total births in Birmingham over a given period. This material was drawn from several sources whose population was known and in which the complete records of anencephalic births were available. RESULTS Isle of Man. This is mainly a rural area with a virtually closed population which is largely homogeneous. Most of the births took place in hospital and the records are complete from about 1935 to 1950. The general incidence of anencephaly was 0.11 per 1,000 births. Wrexham. This is a mixed industrial and agricultural area with a heterogeneous population. The incidence was 0.11 per 1,000 births. Billinge. This is a self-contained coal-mining area and the incidence was 0.22 per 1,000 births. St.

Journal

BJOG : An International Journal of Obstetrics & Gynaecology – Wiley

Published: Dec 1, 1953

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